People with HIV have altered levels of a specific RNA molecule related to both aging and inflammation. This molecule remains altered even with antiretroviral treatment, indicating that their immune system remains affected despite receiving antiretroviral treatment and controlling the infection. The authors of the study, published in the Journal of Microbiology, Immunology, and Infection, suggest that the origin of this alteration is chronic inflammation caused by the infection, regardless of the treatment received by patients. Having this marker can be helpful in monitoring the evolution of patients and the effectiveness of the drugs they take to restore the normal functioning of their immune system.
Researchers from the Hospital del Mar Research Institute have published a new article in Microbiology Spectrum proposing a novel approach to treating pneumonia caused by antibiotic-resistant Pseudomonas aeruginosa bacteria. The study suggests that increasing the dose of the antibiotic colistin may not only be ineffective, but could also increase patient mortality. For this reason, the researchers advocate for using nebulized administration of the treatment instead of intravenous administration. This approach achieves higher concentrations in the lungs, where the infection is located, without causing toxic colistin concentrations in the blood. The World Health Organization considers antibiotic resistance among the top 10 global public health threats.
15/11/2023 - Institutional news
Evidence shows an annual loss of 34.6 million life-years globally due to suicide. In response to this, globally renowned institutions specialized in mental health and suicide research, in collaboration with experts in bioinformatics, have launched PERMANENS, a pioneering European research initiative. The PERMANENS research project is dedicated to create a medical software prototype that supports clinicians in delivering personalized assessments and care to patients arriving at the emergency department with an elevated risk of self-harm or suicide. This precision medicine software will harness the power of artificial intelligence to provide more accurate risk assessments and access to evidence-based information, enabling the identification of effective treatment options tailored to each patient's unique needs and risk profile.
The Lancet Public Health journal has published the results of one of the largest and most up-to-date studies worldwide to evaluate the point prevalence of clinically relevant depressive symptoms.
07/09/2023 - Covid-19
Overall, health has worsened across the population, especially regarding anxiety and depression, as well as pain and discomfort. But the effects of the pandemic have hit educated women especially hard, narrowing their health disparities with population groups with a lower education after initial home confinement. The researchers attribute this development to the negative effect of teleworking on the health of people who worked from home and had to care for family members. At the same time, there may have been a positive effect of government measures to mitigate the economic impact of the pandemic among more disadvantaged groups. The work is part of the MINDCOVID project, and was based on telephone interview surveys of 2,000 people. It is published in the International Journal for Equity in Health.
Més informació "COVID-19 has reduced health inequalities in Spain"
14/07/2023 - Press release
The prevalence of childhood obesity is higher among male participants (14.9%) and in the population aged 8 to 12 years (15.6%). It is confirmed once again that the childhood obesity epidemic in Spain presents a socioeconomic gradient: children enrolled in schools with a lower average income per person have a higher level of obesity. The Gasol Foundation study, carried out with the support of the Hospital del Mar Research Institute, shows a deterioration in eating habits, use of screens, hours of sleep, physical activity, emotional well-being and quality of life among children aged 8 to 16 years in Spain.
14/06/2023 - General information
The Epidemiology and Public Health Program (EPISAP) of the Hospital del Mar Research Institute held its annual meeting on June 7, where the strategic research lines of the groups were shared and the strengths of the program were analyzed. It is worth mentioning the participation in the program of young talented researchers. A consolidated research trajectory together with emerging lines, such as those derived from the COVID-19 pandemic, were highlighted at the meeting. Funding has been received for European projects in areas such as personalized prevention of suicide and depression, measurement of patient reported outcomes (PROs) and the impact on occupational health and safety associated with digital platforms.
Més informació "Annual Meeting of the Epidemiology and Public Health Program"
18/05/2023 - General information
The PROMES-U project aims to improve the mental health of undergraduate students by analyzing the factors that may influence the onset of mental health problems, as well as the implementation and evaluation of online interventions for the promotion of mental health and the prevention of depression and anxiety problems. Follow-up data collection began last May 4 among students who filled out the baseline survey just one year ago, with an email being sent to those who gave up their email address. Upon completion of the questionnaire, they receive a personalized report on their mental health, as well as recommendations on healthy habits and available resources. The data collected will help to improve knowledge about the mental health of students at the university.
Més informació "Data collection is started with the PROMES-U follow-up questionnaire."
24/01/2023 - Institutional news
The study is being led by Dr. Jaume Marrugat, a researcher at the IMIM-Hospital del Mar and coordinator of the Girona Heart Registry (REGICOR). It will analyse the association of the complete genome with the incidence of cardiovascular diseases in people who do not have this pathology and who have been under observation for more than ten years. This is the first project of its kind to be carried out in southern Europe, with a cohort of more than 101,000 participants from all over Spain, and will enable better personalised prevention of these pathologies in the country.
18/11/2022 - General information
A team of researchers from the Hospital del Mar Medical Research Institute has created a model for predicting individual breast cancer risk that could be used to create personalised breast cancer screening strategies. The research, presented at the 13th European Breast Cancer Conference, could make breast screening programmes more effective and ultimately improve survival rates. It could also mean fewer people suffering from 'false positives' (when screening tests indicate cancer, but other tests show there is none) and 'overdiagnosis' (when people are diagnosed and treated for a cancer that is extremely slow growing and has not caused any problems in their lives).
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