IMIM - Institut Hospital del Mar d'Investigacions Mèdiques IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

News

  • 16/09/2021 - Press release

    The Mediterranean diet helps improve cognitive function and memory

    Older adults who are overweight or obese who stick most closely to the Mediterranean diet preserve their cognitive performance and even improve their abilities after three years, according to a study led by researchers at the Hospital del Mar Medical Research Institute and the CIBEROBN, published in the journal Clinical Nutrition.  Memory improvements are proportional to the level of adherence to the Mediterranean diet, weight loss and increased physical activity. At the same time, these changes translate into improvements in people's quality of life.  The work is based on the PREDIMED-PLUS trial and shows that women and people with less education gain less benefit on a cognitive level from this type of dietary intervention. This leads the researchers to support the personalization of these approaches in order to maximize the benefit. 

    Més informació "The Mediterranean diet helps improve cognitive function and memory"

  • 09/09/2021 - General information

    Researchers in IMIM show that cholesterol is fundamental for signal transmission in the human brain

    A study lead by researchers from the Hospital del Mar Medical Research Institute (IMIM) and the Centre for Cellular and Molecular Biology of the Council Of Scientific And Industrial Research (CSIR) published in the Science Advances journal, shows for the first time how cholesterol can interfere with the function of a important receptor present in brain cells - the serotonin receptor.  This finding is of great importance, as it allows to devise new ways to modulate those receptors, which in the future could lead to the development of new drugs to treat diseases of the central nervous system. Cholesterol is an essential component of the neuron membrane. Multiple proteins reside within those membranes, including GPCRs (G-protein coupled receptors). GPCRs are a large receptor family, encompassing serotonin receptors, which act as cellular receptors, detecting outside signals and transmitting towards the cell. Because of this, GPCRs are crucial for correct communications between cells.

    Més informació "Researchers in IMIM show that cholesterol is fundamental for signal transmission in the human brain"

  • 12/08/2021 - Press release

    Way to avoid treatment resistance for one of the most aggressive breast cancers identified

    A study led by doctors and researchers from Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), and CIBER Oncology (CIBERONC) has demonstrated the role a protein, neuregulin, plays in generating resistance to the most common treatment for HER2-positive breast cancer, one of the most aggressive types. The study, published in the journal Clinical Cancer Research, and in which leading Italian researchers Luca Gianni from the Fondazione Gianni Bonnadonna and Giampaolo Bianchini from the IRCCS Ospedale San Raffaele have collaborated, has identified that in patients with high levels of this protein, the success rate with the monoclonal antibody trastuzumab, the first-line drug, drops. Conversely, when combined with another monoclonal antibody, pertuzumab, the situation is reversed and full pathological response levels are restored.

    Més informació "Way to avoid treatment resistance for one of the most aggressive breast cancers identified"

  • 10/08/2021 - General information

    Dr. Miguel Pera, one of the ten best digestive surgeons practising in Catalonia, according to the list of the Institute of Governance and Applied Economics Coordinates.

    The Director of the Healthcare and Medical Area, head of the General and Digestive Surgery Service and co-coordinator of the Clinical and Translational Research Group on Colorectal Neoplasms at the Hospital del Mar Medical Research Institute, is one of the top specialists among Catalan digestive surgeons. Dr. Miguel Pera is one of the ten most outstanding digestive surgeons in Catalonia, according to the ranking published by the Institute of Governance and Economics Coordinates. This institution has published its TOP 100 ranking of the best doctors practising in Catalan hospitals, both public and private. The list has been compiled on the basis of their healthcare, research and teaching activities. 

    Més informació "Dr. Miguel Pera, one of the ten best digestive surgeons practising in Catalonia, according to the list of the Institute of Governance and Applied Economics Coordinates."

  • 06/08/2021 - Press release

    $200,000 grant for lung cancer research at Hospital del Mar

    A Hospital del Mar project to determine new prognostic and predictive markers that could be beneficial in metastatic small cell lung cancer treatment, using genetic analysis techniques, has been awarded $200,000 from the Oncomine Clinical Research Grant programme, promoted by the US-based multinational biotech company Thermo Fisher Scientific, which supports research that enables advances in the field of molecular patient profiling, with the aim of improving clinical outcomes. The research was led by Dr. Edurne Arriola, head of the lung cancer section in the Medical Oncology Service and a researcher at the Hospital del Mar Medical Research Institute (IMIM), and Dr. Beatriz Bellosillo, head of the Medical Oncology Service and also an IMIM researcher. To undertake the project, they will analyse samples from 300 patients with this pathology, collected over the last 10 years. The research will focus on evaluating the potential of the liquid biopsy technique, which can detect DNA from tumour cells in the blood, to monitor the disease and its evolution, as well as detecting potential biomarkers of treatment benefit and predictors of long-term prognosis.

    Més informació "$200,000 grant for lung cancer research at Hospital del Mar"

  • 29/07/2021 - Press release

    Mechanism that triggers brain neurone response revealed

    Researchers from the G-protein-coupled receptor-based drug development research group at the Hospital del Mar Medical Research Institute (IMIM) have been able to verify, with a degree of precision never before achieved, how the process that triggers the response of neurones in the brain occurs. This is an essential mechanism for understanding how moods or even processes such as addictions are produced, and in which neurotransmitters, molecules that help transmit information between neurones through specialised receptors, the G protein-coupled receptors (GPCRs), play a vital role. "Neurotransmission is one of the most crucial physiological processes, as its dysregulation can result in various neuropsychiatric disorders", explains Dr. Jana Selent, principal author of the study, published in the journal Chemical Science, and coordinator of the research group that led the work. Very small changes in how information is transmitted by these molecules can trigger different reactions in the brain, some of which are linked to behaviour, addictions and moods.

    Més informació "Mechanism that triggers brain neurone response revealed"

  • 28/07/2021 - General information

    "La mare de la ciència", the new PRBB scientific outreach podcast, today with Toni Celià-Terrassa

    On July 19 the Barcelona Biomedical Research Park (PRBB) launched a new science outreach product, "La mare de la ciència", a podcast in Catalan where you can "listen to science" done at the Park. During the second half of July the six episodes that make up the first season will be released. Today, July 28th, the podcast of Toni Celià-Terrassa, group leader of the Cancer Stem Cells and Metastasis Dynamics group, will be launched and will help us to decipher metastasis. This is a narrative podcast in short format, where Marta Vila, from the PRBB's communication department, leads us through the research and stories of six researchers from the Park's centres. A very personal and close look to the science that is done in the PRBB and the people behind it.

    Més informació ""La mare de la ciència", the new PRBB scientific outreach podcast, today with Toni Celià-Terrassa"

  • 21/07/2021 - Press release

    Having higher levels of omega-3 acids in the blood increases life expectancy by almost five years

    Levels of omega-3 fatty acids in the blood are as good a predictor of mortality from any cause as smoking, according to a study involving the Hospital del Mar Medical Research Institute (IMIM), in collaboration with The Fatty Acid Research Institute in the United States and several universities in the United States and Canada. The study, published in The American Journal of Clinical Nutrition, used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971. Researchers have found that omega-3 levels in blood erythrocytes (the so-called red blood cells) are very good mortality risk predictors. 

    Més informació "Having higher levels of omega-3 acids in the blood increases life expectancy by almost five years"

  • General information

    The Anti-Doping Laboratory of Catalonia collaborates with the Tokyo Olympic Laboratory

    Two professionals from the Laboratory will travel to the Japanese capital to support the anti-doping work that will take place during the Olympic Games, which begin on July 23. The Hospital del Mar Institute for Medical Research (IMIM) will once again be Olympic. Two of the Anti-Doping Laboratory of Catalonia professionals at IMIM will work at the Olympic Games Laboratory in Tokyo, which starts this July 23. Sergi Coll and Lídia Requena will travel to Tokyo to work there until August 10. Sergi Coll specializes in detecting anabolic steroids, and Lídia Requena specializes in detecting hormones (erythropoietin, growth hormone ...) and blood transfusions.

    Més informació "The Anti-Doping Laboratory of Catalonia collaborates with the Tokyo Olympic Laboratory"

  • Press release

    A new approach to metastatic melanoma discovered

    Combining chemotherapy with a BRAF oncogene inhibitor proves effective at treating this disease. The study, published in the journal Oncogene, was led by researchers from the Hospital del Mar Medical Research Institute, Hospital del Mar and CIBERONC. This alternative paves the way towards a new approach for patients affected by this type of tumor, which has no cure in the most advanced stages or cases of relapse.

    Més informació "A new approach to metastatic melanoma discovered"

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Marta Calsina Freixas(ELIMINAR)

Tel:
(+34) 93 316 06 80

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08226 Barcelona

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