IMIM - Institut Hospital del Mar d'Investigacions Mèdiques IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Epidemiology and public health

Tornar

Research lines 2018

Cancer

  • Quality, effectiveness and costs of breast and colon cancer screening programs.

  • Personalization of breast cancer screening program. To develop new predictive models of individual risk of breast cancer in women participating in mammographic breast cancer screening based on individual risk factors to estimate the impact of the polygenic risk score as a risk factor for breast cancer

  • To estimate health care needs and resources for long term breast cancer survivors surveillance

  • Clinical and molecular epidemiology of exocrine pancreatic cancer.

  • Causes and consequences of diagnostic and therapeutic delays in cancer.

  • Comparative effectiveness and cost-utility of localized prostate cancer therapies.

  • Methodological issues in longitudinal studies on body burden of environmental pollutants and pancreatic cancer risk.

  • Toenail concentrations of trace elements and occupational history in pancreatic cancer.

Cardiovascular 

  • Determination of incidence, mortality and case-fatality trends in myocardial infarction (MI) and distribution of cardiovascular (CV) risk factors.

  • Development of new systems to establish myocardial infarction and acute coronary syndrome population incidence with administrative data (CMBD and mortality data) in Girona and Catalonia.

  • Improvement of predictive capacity of cardiovascular risk functions for primary prevention of cardiovascular diseases.

  • Physical activity measurement and its relationship with cardiovascular health and mechanisms.

  • Analysis of common and rare genetic and epigenetic variants (focused on microRNA and gene methylation) associated with cardiovascular traits; Gene by Environment interaction in CV diseases.

  • New biomarkers of prognosis and prediction of cardiovascular diseases, with particular emphasis in epigenetics (DNA methylation and microRNAs) and in the analysis of their causal or mediating role.

  • Apply the benchmarking function developed in the EURHOBOP and EUROTRACS EC projects led by EPISAP groups, to Catalan hospitals in agreement with AQUAS.

  • Development and evaluation of new methods to prevent cardiovascular diseases by using information technologies

  • Effectiveness of drugs and intervention in the prevention and treatment of cardiovascular diseases.

Environment 

  • Health effects of Exposome.

  • Birth cohorts in Europe.

  • Environmental, occupational and genetic factors related to cancer, immune, respiratory disease and child health.

  • Exposure assessment using new biomedical technologies and implementing complex statistics and bioinformatics methods.

  • Environmental exposures in early life and neurodevelopment, obesity and metabolic syndrome, and allergy and asthma.

  • NCDs and Environment to low and middle income countries.

  • Assessing the population distribution and impact on human health of Persistent Organic Pollutants (POPs) and other environmental chemical agents.

  • Global urban environments. Built environment and health.

  • Body concentrations of persistent pollutants and unhealthy metabolic phenotypes in normal-weight, overweight and obese individuals.

Equity

  • Patterns and causes of health inequities embedded in urbanization processes.

  • Urban Planning and the Right to the Healthy Cities.

  • In-depth spatial and quantitative analysis of the scope and magnitude of green gentrification trends in 40 cities in the US, Canada, and Europe.

  • Health and wellbeing effects of green rooftops for people with disabilities: effects and potential mechanisms.

  • Advanced theoretical and measurement methods of objective and perceived gentrification for public health research.

  • Health effects of gentrification and displacement, pathways, and mechanisms

Health care 

  • Advanced measurement methods for patient-reported outcomes (PROMs).

  • Information systems for assessment of costs per patient and risk adjustment.

  • New strategies for improving quality and patient safety.

  • Tools and methods for improving health services research, including discrete event simulation models.

  • Comparative effectiveness and cost-utility of therapies for most burdensome conditions (asthma, cancer, depression, low-back pain, and MI, among others).

  • Comorbidity and health services use among breast cancer survivors.

  • Access to care and changes in urban healthcare delivery systems (healthcare gentrification) (cross with equity).

Infertility

  • Effects of air pollution on fertility and sperm quality.
  • Effects of air pollution and ovarian reserve.
  • Effects of assisted  reproduction technologies on perinatal outcomes.

Mental health

  • Frequency and risk factors of common mental disorders and suicide in general population and among university students.

  • Distribution and correlates of perceived health and psychological well-being in the general population.

  • Association of mental disorders and physical chronic conditions.

  • Prevalence trends of drug use and associated factors.

  • Psychiatric comorbidity, interpersonal violence and mortality associated to drug use.

  • Incidence of suicide attempt and reattempt and evaluation of interventions in high risk of suicide individuals.

  • Impacts of gentrification and displacement on mental health and wellbeing (Cross with equity).

Nutrition 

  • Obesity and diabetes: epidemiology and prevention across the life span.

  • High density lipoproteins (HDL) functionality and atherogenic lipoproteins linked to nutrition. Predictive value of HDL functions for chronic degenerative diseases, such as cardiovascular, cancer, and neurodegenerative ones.

  • Nutrigenomics: changes in gene expression attributable to nutrients and foods.

  • Interaction between diet and intestinal flora.

  • Halo effect of a life-style intervention on the familiar nucleus.

  • Nutrition intervention studies.

  • Nutritional epidemiology and childhood obesity.

Nursing care

  • Nurse empowerment: impact of BPSO program on nurse's work environment and nurse evidence based practice.

  • PROMs -Patient-Reported Outcomes and PREMs -Patient-reported experiences (PREMs).

  • Impact nursing care on patient and caregivers and health systems: impact of specific nursing care programs on: QOL in dialysis patients; patients with epilepsy.

  • Development of a decision algorithm of the PICC

  • Analysis of the PSMAR Electronic Nursing records

Occupation & Unemployment

  • Labor market trajectories and permanent disability and mortality.

  • Occupational diseases recognition.

  • Working condition surveys in Latin America and Caribbean.

  • Cluster-randomized controlled trial of a multicomponent workplace intervention to improve musculoskeletal health in hospital workers (INTEVAL_plus).

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