IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

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  • Parts of the genome without a known function may play a key role in the birth of new proteins

    17/09/2014

    Researchers in Biomedical Informatics at IMIM (Hospital del Mar Medical Research Institute) and at the Universitat Politècnica de Catalunya (UPC) have recently published a study in eLife showing that RNA called non-coding (IncRNA) plays an important role in the evolution of new proteins, some of which could have important cell functions yet to be discovered.

    Ribosomes produce proteins from the instructions found in an RNA molecule. However, only 2% of the human genome is RNA containing information for the synthesis of proteins, meaning it is coding. Other parts of the genome that are transcribed could be “evolutionary noise”, parts of the DNA that are copied to RNA randomly but with no concrete biological function. Now, a new sequencing technique has revealed that many of these transcripts (IncRNAs) may also translate into proteins, leading to an intense debate.

    Read more sobre "Parts of the genome without a known function may play a key role in the birth of new proteins"

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Institut Hospital del Mar d'Investigacions Mèdiques

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