Laboratory of Neuropharmacology
Associated group
The Laboratory of Neuropharmacology (NeuroPhar) is a UPF research group associated with the IMIM. NeuroPhar studies the neurobiological substrate of drug addiction, pain, cognitive deficits, affective and eating disorders. The main interest of this research group is the development of research lines aimed at the identification of new therapeutic targets in the central nervous system.
The Laboratory of Neuropharmacology is particularly interested in the involvement of the endogenous opioid and cannabinoid systems in these pathological processes.
Main Publications with IMIM
• Maldonado R, Baños JE, Cabañero D. Usefulness of knockout mice to clarify the role of the opioid system in chronic pain. Br J Pharmacol 2018; 175(14): 2791-2808. IF 6.81. D1.
• Gutiérrez-Martos M, Girard B, Mendonça-Netto S, Perroy J, Valjent E, Maldonado R, Martín-Mateo M. Cafeteria diet induces neuroplastic modifications in the nucleus accumbens mediated by microglia activation. Addict Biol 2018; 23(2): 735-749. IF 5.578. Q1.
• Manzanares J, Cabañero D, Puente N, García-Gutiérrez MS, Grandes P, Maldonado R. Role of the endocannabinoid system in drug addiction. Biochem Pharmacol 2018; 157: 108-121. IF 4.235. Q1.
Ongoing Research Projects with IMIM
• Characterisation of novel suppressors of neurodegeneration in myotonic dystrophy type 1 (DM1)
- Financing institution: Fundació La Marató TV3 (20143530-31)
- Period: from 2015 to 2018
- Principal investigator: Robledo, Patricia
- Member of the research team: Maldonado, Rafael
Participation in Research Networks
• Complications of stimulant use disorder. Redes temáticas de investigación cooperativa en salud (RETICS)
- Financing institution: Instituto de Salud Carlos III (RD16/0017/0020) (Red de trastornos adictivos, RTA)
- Period: from 2017 to 2021
- Coordinator: Rodríguez de Fonseca, Fernando (Instituto Ibima de Málaga - Hospital Regional Universitario de Málaga)
- Programme leader: Torrens Marta (IMIM)
- Principal investigator: Maldonado, Rafael (UPF)
• Medical complications of alcohol use disorder. Redes temáticas de investigación cooperativa en salud (RETICS)
- Financing institution: Instituto de Salud Carlos III (RD16/0017/0010) (Red de trastornos adictivos, RTA)
- Period: from 2017 to 2021
- Coordinator: Rodríguez de Fonseca Fernando (FIMABIS)
- Programme leader: Rodríguez de Fonseca Fernando (Instituto Ibima de Málaga - Hospital Regional Universitario de Málaga)
- Principal investigators: Torrens, Marta (IMIM); Maldonado, Rafael (UPF)
Theses
• Kossatz de Mello E. Neuroprotective mechanisms of CB2 cannabinoid receptors and PPAR-α in hypoxia/ischemia-induced brain damage. Universitat Pompeu Fabra.
- Directors: Robledo Montoya, Patricia (IMIM), Maldonado López, Rafael (UPF)
- Date of defense: 08/06/2018
C/ Doctor Aiguader, 88
08003 Barcelona
(+34) 93 316 04 00
info@imim.es