IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Breast Cancer and Stem Cell Research

Cell

The Celià-Terrassa’s Lab focuses on understanding the breast cancer stem cells (bCSCs) and their interplay with the microenvironment during tumor initiation and metastasis colonization. In particular, we are interested on studying the molecular mechanisms underlying Cancer Stem Cell (CSC) cellular plasticity leading tumor progression, chemorresistance and relapse, as a major challenge to efficiently target breast cancer.

Main streamlines of research are:

  1. the CSCs’ immune interplay and immunotherapy approaches in triple-negative breast cancer; 
  2. the cellular plasticity engaged by dynamic bidirectional epithelial-to-mesenchymal transitions (EMT) during the latter steps of metastasis.

Our lab is framed at the intersection of the basic stem cell & cancer biology research with the clinical research at the Hospital del Mar, this unique translational configuration aims to quickly bridge our basic discoveries to immediate clinical applications for breast cancer therapeutics.

https://twitter.com/TCeliaTerrassa

Contact

Lab Leader:
Toni Celià-Terrassa

Tel:
93 3160434

Dr. Aiguader, 88, 2ª Planta
08003 Barcelona

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