Barcelona Research Infertility Group

Research group

Group Leader

Miguel Ángel Checa Vizcaíno

Biomedical care in fertility disorders has gained recognition as has the diagnosis and treatment of a disease, infertility, where an essential biological function to achieve a life plan is impaired. Taking this into consideration, since 1995, the diagnosis and treatment of infertility has been included as a basic benefit within the Catalog of Services of the National Health System (Royal Degree 63/1995, 20 January, health benefits under the social security program).

The overall objective is to carry out research in a multidisciplinary group, and to combine collective expertise to extend knowledge of the loss of fertility observed in our society, as well as to offer preventive, diagnostic and therapeutic solutions that will either minimize the impact of this disorder or successfully overcome it.

Epidemiological research aims to analyze various air pollutants and environmental factors and assess their impact on reproductive outcomes, including sperm quality, which may lead to guidelines for the prevention or reduction of human exposure to environmental pollutants.

Clinical research in human model will allow us to assess strategies that may potentially improve reproductive functions and thereby increase live birth rate when ART are required.

Evidence Based Medicine research: We collaborate with the Cochrane Gynecology and Fertility group evaluating the evidence in reproductive medicine in international studies. We aim to develop translational recommendations for best clinic practice.





Mireia González Comadran (Researcher)

María Prat Om (Researcher)

Ana Beatriz Robles Corchado (Researcher)


Main Publications

• Lattes K, Checa MA, Vassena R, Brassesco M, Vernaeve V. There is no evidence that the time from egg retrieval to embryo transfer affects live birth rates in a freeze-all strategy. Hum Reprod 2017; 32(2): 368-374. IF 5.02. D1.

• Vidal M, Vellvé K, González-Comadran M, Robles A, Prat M, Torné M, Carreras R, Checa MA. Perinatal outcomes in children born after fresh or frozen embryo transfer: a Catalan cohort study based on 14,262 newborns. Fertil Steril 2017; 107(4): 940-947. IF 4.373. Q1.

• González-Comadran M, Schwarze JE, Zegers-Hochschild F, Souza MD, Carreras R, Checa MÁ. The impact of endometriosis on the outcome of Assisted Reproductive Technology. Reprod Biol Endocrinol. 2017 Jan 24; 15(1): 8. Q2.

Ongoing Research Projects

• Impacto de la exposición aguda a contaminantes atmosféricos sobre los resultados de la fecundación in vitro

- Fondo de Investigación Sanitaria. ISCIII (PI13/00454)

- From 2014 to 2018

- Principal investigator: Checa Vizcaíno, Miguel Ángel


Group’s Recognitions

• Officially recognised as a precompetitive research group by the Generalitat de Catalunya: Grup de Recerca de Medicina Reproductiva i Fetal (2017-2019)

- Agència de Gestió d'Ajuts Universitaris i de Recerca (SGR 420)

- Principal investigator: Checa Vizcaíno, Miguel Ángel

Clinical Trials Signed in 2017

• SPIRIT 1: Estudio en fase III, internacional, aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y la seguridad de relugolix administrado con y sin estradiol y acetato de noretisterona en dosis bajas en mujeres con dolor asociado a endometriosis

- Register: Myovant Sciences GmbH

- Principal investigator: González Comadran, Mireia

• A multi-centre, randomised, double-blind, placebo-controlled trial to investigate the efficacy and safety of two concentrations of PKB171 against placebo in couples with asthenozoospermia who wish to conceive

- Register: Prokrea BCN S.L

- Principal investigator: Checa Vizcaíno, Miguel Ángel



• Lafuente R. Effect of enviromental factors in sperm quality. Autonomous University of Barcelona

- Directors: Checa Vizcaíno, Miguel Ángel; Jacquemin, Benedicte

- Date of defense: 13/7/2017




C/ Doctor Aiguader, 88

08003 Barcelona

(+34) 93 316 04 00